Research

Help from herpes? Coinfection induces acyclovir to inhibit HIV

Published in AIDS Weekly, September 22nd, 2008

A surprising interaction may enable development of new HIV treatment strategies by exploiting infection with multiple pathogens. The research, published by Cell Press in the September 11th issue of the journal Cell Host and Microbe, demonstrates that a drug commonly used to treat herpes directly suppresses HIV in coinfected tissues and thus may be beneficial for patients infected with both viruses.

Commonly, individuals infected with HIV are infected also with other microbes. Infection with human herpesvirus (HHV), especially with herpes simplex virus-2 (HSV-2), is often associated with HIV. These HHV infections may be either active or dormant, but HIV infection makes...

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Source: AIDS Weekly (2008-09-22)

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