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HIV/AIDS

New findings in HIV/AIDS described by E. Ferrer and co-researchers

Published in AIDS Weekly, October 27th, 2008

According to a study from Barcelona, Spain, "We evaluated a single-class quadruple nucleoside/nucleotide regimen in a 96-week prospective one-arm pilot study in adult HIV-infected naive patients with CD4 > 100 cells/mu l. Standard zidovudine/lamivudine/abacavir and tenofovir doses were given. Virologic efficacy was evaluated by intent-to-treat (ITT), switch = failure and on-treatment (OT) analyses."

"A total of 54 patients were included (median CD4 count 254 cells/mu l, VL 79,706 copies/ml). A median drop in VL of 2 log at 14 days and > 3 log since week 12 was observed. A total of 34/54 (63%) patients (ITT) and 34/39 (87%) patients (OT) had VL < 50 copies/ml at...

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