Published in AIDS Weekly, October 27th, 2008
"This apoptosis is notably mediated by the interaction of Tat with microtubules, which are dynamic components essential for cell structure and division. Tat binds two Zn2+ ions through its conserved cysteine-rich region in vitro, but the role of zinc in the structure and properties of Tat is still controversial. To investigate the role of zinc, we first characterized Tat apo- and...
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