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Pharmacokinetics
Reports outline pharmacokinetics study results from M. Schöller-Gyüre et al
November 3rd, 2008
Fresh data on pharmacokinetics are presented in the report 'Effects of different meal compositions and fasted state on the oral bioavailability of etravirine.' In this recently published study, investigators in Mechelen, Belgium conducted a study "To determine the effects of various meal compositions and the fasted state on the pharmacokinetics of etravirine, a nonnucleoside reverse transcriptase inhibitor. Phase I, open-label, randomized, repeated single-dose, three-period crossover trial." "Clinical pharmacology unit. Two parallel panels of 12 human immunodeficiency virus (HIV)-negative, healthy, male volunteers. Twenty volunteers completed the study; three withdrew...
Source: AIDS Weekly (2008-11-03)
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