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Scripps Research Institute



Scripps research team sheds light on immune system suppression



November 3rd, 2008

The work was reported in the October 16 issue of the journal Cell Host & Microbe.

The study described the suppression of this immune response in mice infected with lymphocytic choriomeningitis virus, pointing to potential new avenues for the development of drug treatments for immunosuppressive diseases in humans.

"It's the first demonstration that a virus causes suppression of the interferon response in vivo," says the paper's senior author Michael Oldstone, a Scripps Research professor and a pioneer in immune system studies. "This model explains how a secondary infection can be caused by a normal virus infection and this provides the guide for what...


Source: AIDS Weekly (2008-11-03)

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