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Cancer Vaccines

HIV'S disguises no match for Bionic Assassins

Published in AIDS Weekly, November 24th, 2008

HIV is a master of disguise, able to rapidly change its identity and hide undetected in infected cells. But now, in a long-standing collaborative research effort partially-funded by the Wellcome Trust, scientists from Oxford-based Adaptimmune Limited, in partnership with the Universities of Cardiff and Pennsylvania, have engineered immune cells to act as "bionic assassins" that see through HIV's many disguises.

The findings of the study, published online in the journal Nature Medicine, may have important implications for developing new treatments for HIV and slowing – or even preventing – the onset of AIDS. Over 33 million people were estimated to be living with HIV...

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