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HIV/AIDS

New research on HIV/AIDS from Chelsea and Westminster Hospital NHS Trust summarized

Published in AIDS Weekly, January 5th, 2009

According to recent research published in the journal AIDS Research and Human Retroviruses, "Data from two Phase IIb trials, POWER 1 and 2 (TMC114-C213 and C202), were pooled to examine the effect of baseline viral susceptibility on response to control protease inhibitors [CPI(s)] compared with response to darunavir (TMC114) given with low-dose ritonavir (darunavir/r) in treatment-experienced HIV patients. POWER 1 and 2 were randomized, controlled Phase IIb trials with a similar design."

"Patients with one or more primary PI mutations and HIV-1 RNA > 1000 copies/ml were randomized to receive an optimized background regimen plus darunavir/r or CPI(s). POWER 1...

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