HIV/AIDS
Data from Y. Qian and colleagues advance knowledge in HIV/AIDS
Published in AIDS Weekly, February 9th, 2009
According to a study from Kunming, People's Republic of China, "Polymorphisms of CCR5, CCR2, SDF, and CX3CR1 were reported to be involved in HIV-1 infection or the development of disease progression to AIDS. Cohort studies showed that CCR5-Delta 32, SDF1-3'A, and CCR2-64I were protective, which could provide resistance to HIV-1 infection or delay disease progression, although the effect of SDF1-3'A homozygosity in the later stage of progression to AIDS was still controversial."
"The two SNPs of CX3CR1-249I and 280M were independent risk factors, which could accelerate the progression to AIDS. In this study, we surveyed the frequency distributions of the five alleles in...
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Source: AIDS Weekly (2009-02-09)
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