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HIV/AIDS Therapy

Reports from J.L. Meynard et al highlight recent research in HIV/AIDS therapy

Published in AIDS Weekly, February 23rd, 2009

Scientists discuss in 'Influence of liver fibrosis stage on plasma levels of efavirenz in HIV-infected patients with chronic hepatitis B or C' new findings in HIV/AIDS. According to a study from Paris, France, "Liver function is a key component of efavirenz metabolism and might be altered in severe liver fibrosis induced by HIV/chronic hepatitis co-infection. However, data evaluating the impact of liver fibrosis stages on the plasma efavirenz level are lacking."

"In this study, conducted in 134 HIV-infected patients [77, 35 and 22 HIV mono-infected, HIV/hepatitis C virus (HCV) co-infected and HIV/hepatitis B virus (HBV) co-infected, respectively] treated with efavirenz...

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