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Antifungals

New antifungals research from Chinese University of Hong Kong outlined

Published in AIDS Weekly, February 23rd, 2009

"To isolate and characterize an antifungal peptide from the seeds of Brassica parachinensis L.H.Bailey. An antifungal peptide designated as brassiparin was isolated," scientists in Hong Kong, People's Republic of China report.

"It exhibited a molecular mass of 5716 Da. It potently inhibited mycelial growth in a number of fungal species including Fusarium oxysporum, Helminthosporium maydis, Mycosphaerella arachidicola and Valsa mali. The antifungal activity of brassiparin toward M. arachidicola exhibited pronounced thermostability and pH stability. It inhibited proliferation of hepatoma (HepG2) and breast cancer (MCF7) cells and the activity of HIV-1 reverse...

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