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HIV/AIDS

New HIV/AIDS findings from X. Bi and co-researchers published

Published in AIDS Weekly, March 30th, 2009

According to a study from Tokyo, Japan, "The frequency of Treg is reported to be higher in patients with chronic HIV type 1 (HIV-1) infection and CD45RA(+) Treg exist in normal adults. in this study, we found a lower absolute number (15 cells/mu L) but a higher proportion (16.2%) of FOXP3(+) cells (Treg) in the CD4(+) population in treatment-naive HIV-1 patients with low CD4 (<200cells/mu L) counts than in those with high CD4 counts (34 cells/mu L and 9.3%) or healthy adults (48 cells/mu L and 7.5%). In HIV-1 patients, CD45RA(+)CCR7(+), CD45RA(-)CCR7(+), and CD45RA(-)CCR7(-) subsets were identified in the Treg population, and the proportion of CD45RA(-)CCR7(-) Treg was higher (57.9%) in...

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