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HIV/AIDS Co-Infection

Data from Kagoshima University advance knowledge in HIV/AIDS co-infection

Published in AIDS Weekly, April 6th, 2009

According to recent research from Kagoshima, Japan, "To determine the relationship between the human immunodeficiency virus type 1 (HIV-1) encephalitis (HIVE) and diffuse polio-dystrophy in the acquired immunodeficiency syndrome dementia complex, we examined the neuropathologic features in brain autopsy tissue specimens of HIV-1-infected patients with (n = 11) or without HIVE (n = 9). The brains were free of opportunistic diseases and major cerebrovascular lesions."

"In both groups, there was diffuse microglial activation, astrocytic gliosis, and decreased excitatory amino acid transporter 2 (EAAT-2) immunoreactivity. These changes did not correlate either with the...

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