HIV/AIDS
Research from University of Siena yields new findings on HIV/AIDS
Published in AIDS Weekly, April 13th, 2009
"A series of S-DABO analogues, where the double bond in the C2-substituent is replaced by an enantiopure isosteric cyclopropyl moiety, has been synthesized, leading to the identification of a potent lead compound endowed with picomolar activity against RT (wt) and nanomolar activity against selected drug-resistant mutants. Molecular modeling calculation, enzymatic studies, and surface plasmon resonance experiments allowed us to rationalize...
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Source: AIDS Weekly (2009-04-13)
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