HIV/AIDS

Research on HIV/AIDS discussed by L. Tombuyzer and co-researchers

Published in AIDS Weekly, April 20th, 2009

"Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are an important component of antiretroviral therapy for HIV type-1 (HIV-1)-infected patients. Developrnent of NNRTI resistance can lead to treatment failure and is conferred by the presence of specific resistance-associated mutations (RAMs) in the reverse transcriptase," scientists writing in the journal Antiviral Therapy report.

"In addition to the widely used list of NNRTI RAMs provided by the International AIDS Society-USA HIV-1 Drug Resistance Mutation Group, which were identified on the basis of clinical experience with the approved NNRTIs, a more comprehensive list of NNRTI RAMs is needed to guide...

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Source: AIDS Weekly (2009-04-20)

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