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HIV/AIDS

Reports from University of Sydney describe recent advances in HIV/AIDS

Published in AIDS Weekly, April 27th, 2009

According to recent research from Westmead, Australia, "In a recent summary of integrase sequences, primary integrase inhibitor mutations were rare."

"In a review of integrase inhibitor-naive Australian HIV-1 sequences, primary mutations were not identified, although the accessory mutation G140S was detected. A link with previous antiretroviral therapy, intra-subtype B divergence across the integrase gene and transmission of integrase polymorphisms were also noted," wrote S.J. Vanhal and colleagues, University of Sydney.

The researchers concluded: "Based on these findings, we would recommend ongoing surveillance of integrase mutations, and integrase...

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