HIV/AIDS

Research from J.M. Vazquezguillen and colleagues has provided new data on HIV/AIDS

Published in AIDS Weekly, May 11th, 2009

According to recent research from Nuevo Leon, Mexico, "The main access route for human immunodeficiency virus (HIV) into the lymph nodes is through the mucosa. Once there, dendritic cells (DCs) are the first cells to interact with the virus."

"Then, DCs can uptake and transport to the lymph nodes, beginning a disseminated infection. Interaction between the virus and DCs is mediated by the receptor DC-SIGN. This study seeks to determine any relationship between HIV-AIDS immunopathology and DC-SIGN expression levels in DCs from typical, rapid, and slow progressors. A DC separation system was implemented using peripheral blood mononuclear cells from infected subjects. The...

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Source: AIDS Weekly (2009-05-11)

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