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HIV/AIDS
Studies by J.M. Waters and co-authors describe new findings in HIV/AIDS
June 15th, 2009
According to recent research published in the journal Antiviral Therapy, "Antiretroviral therapy that targets HIV type-1 (HIV-1) reverse transcriptase (RT) can be linked to mutations in the thumb-connection (amino acids [AA] 241-426) and RNase H (AA 427-560) domains, which could affect drug resistance. Genotypical and statistical analyses were performed on HIV-1 RT from 100 antiretroviral treatment-naive and 248 antiretroviral treatment-experienced patients, the majority of whom were infected with HIV-1 subtype B. The RT region was analysed in three parts: the polymerase (AA 1-240), thumb-connection (AA 241-426) and RNase H (AA 427-560) domains." "The polymerase...
Source: AIDS Weekly (2009-06-15)
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