HIV/AIDS

Research from B.R. Okeefe and co-authors in the area of HIV/AIDS published

Published in AIDS Weekly, June 15th, 2009

"To prevent sexually transmitted HIV, the most desirable active ingredients of microbicides are antiretrovirals (ARVs) that directly target viral entry and avert infection at mucosal surfaces. However, most promising ARV entry inhibitors are biologicals, which are costly to manufacture and deliver to resource-poor areas where effective microbicides are urgently needed," scientists in the United States report.

"Here, we report a manufacturing breakthrough for griffithsin (GRFT), one of the most potent HIV entry inhibitors. This red algal protein was produced in multigram quantities after extraction from Nicotiana benthamiana plants transduced with a tobacco mosaic virus...

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Source: AIDS Weekly (2009-06-15)

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