Published in AIDS Weekly, June 22nd, 2009
The infamous mutability of viruses has long challenged antiviral drug developers, but complete genome sequences are now known for thousands of viruses, and the viral proteins encoded in these sequences are being used as targets for novel antiviral development. Viruses originated early during the evolution of life and have survived by their ability to mutate key genetic sequences in order to evade the defense systems of their hosts.
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