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HIV/AIDS

Findings from S. Sen and co-authors broaden understanding of HIV/AIDS

Published in AIDS Weekly, July 20th, 2009

"The HIV-1 gp41 has been identified as an important target for the immune response, for the development of antiviral and vaccine strategies, and for epidemiologic studies. This study describes the HIV-1 env gp41 region mutations, associated with enfuvirtide (ENF) resistance, in proviral DNA from PBMCs in antiretroviral treatment-naive individuals from Pune, India," scientists writing in the journal AIDS Research and Human Retroviruses report.

"Twenty-one antiretroviral drug-naive chronically HIV-1-infected individuals were enrolled. The study sequences belonged to subtype C (n = 17), subtype A1 (n = 2), and CR_AE (n = 2). In subtype B-infected individuals, the...

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