HIV/AIDS

Tor Vergata University details research in HIV/AIDS

Published in AIDS Weekly, August 10th, 2009

"The protease inhibitor atazanavir (ATV) can be used either boosted by ritonavir (ATV300/r) or unboosted (ATV400). To date, however, genotypic resistance scores (GRSs) have been developed only for boosted-ATV," scientists in Rome, Italy report.

"We have determined GRS associated with virologic response (VR) for both ATV300/r and ATV400 in highly pre-treated HIV-1 infected patients. We analyzed the results of genotypic tests available 0-3 months before the initiation of an ATV-containing regimen in 159 patients with HIV-RNA a parts per thousand yen 500 copies/ml (ATV300/r group: 74; ATV400 group: 85) who were enrolled in the CARe study through an Early Access Program....

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Source: AIDS Weekly (2009-08-10)

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