HIV/AIDS

Reports from University of Modena advance knowledge in HIV/AIDS

Published in AIDS Weekly, August 10th, 2009

"No data are available on the use of atazanavir (ATV) in patients with end-stage liver disease (ESLD), and guidelines discourage its use in this setting. The objective of our study was to evaluate the efficacy and safety of unboosted ATV in patients infected with HIV and suffering from ESLD who had been screened for orthotopic liver transplantation (OLTx)," researchers in Modena, Italy report.

"This was a single-arm, 24-week pilot study. Atazanavir-na < ve patients undergoing a highly active antiretroviral therapy were switched to ATV 400 mg daily plus two non-thymidine nucleoside reverse transcriptase inhibitors. Fifteen patients (ten males and five females, age...

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Source: AIDS Weekly (2009-08-10)

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