Hepatitis C Virus

New hepatitis C virus study findings have been published by P. Qiu and colleagues

Published in AIDS Weekly, August 17th, 2009

"A major challenge to successful antiviral therapy is the emergence of drug-resistant viruses. Recent studies have developed several automated analyses of HIV sequence polymorphism based on calculations of selection pressure (K-a/K-s) to predict drug resistance mutations," investigators in the United States report.

"Similar resistance analysis programs for HCV inhibitors are not currently available. Taking advantage of the recently available sequence data of patient HCV samples from a Phase II clinical study of protease inhibitor boceprevir, we calculated the selection pressure for all codons in the HCV protease region (amino acid 1181) to identify potential resistance...

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Source: AIDS Weekly (2009-08-17)

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