Published in AIDS Weekly, September 7th, 2009
"In this study, the impact of Leu-214 on replication capacity and resistance to zidovudine (ZDV) of viruses containing TAM1 or TAM2 was determined. Leu-214 decreased the growth rate of viruses bearing Tyr-215, as well as their resistance to ZDV," wrote M.C. Puertas and colleagues.
The researchers concluded: "This observation was confirmed by structural and...
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