Life Sciences

Scientists at University of Magdeburg publish new data on life sciences

Published in AIDS Weekly, September 14th, 2009

"Opioids are widely used for the treatment of severe pain. However, it is also known that opioids, in particular morphine, cause immunosuppression," scientists writing in the Journal of Immunology report.

"Therefore, their use may complicate treatment of persons with an already impaired immune system, e.g., patients suffering from cancer or AIDS. We investigated the mechanisms of opioid-induced immunosuppression in primary human T lymphocytes and the human T cell line Jurkat. We demonstrated that morphine and the endogenous opioid beta-endorphin inhibited the transcription of IL-2 in activated human T lymphocytes as well as the activation of the transcription...

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Source: AIDS Weekly (2009-09-14)

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