Duke University Medical Center

Discovery leads to rapid mouse 'personalized trials' in breast cancer

Published in AIDS Weekly, September 21st, 2009

One person's breast cancer is not the same as another person's, because the gene mutations differ in each tumor. That makes it difficult to match the best therapy with the individual patient.

Using a finding that the genetic complexity of tumors in mice parallels that in humans, researchers at the Duke University Institute for Genome Sciences and Policy and Duke University Medical Center are starting trial studies in mice, just like human clinical trials, to evaluate whether understanding tumor diversity can improve cancer treatment.

"Giving everyone the same few current treatments doesn't take the very different types of tumors into account," said...

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Source: AIDS Weekly (2009-09-21)

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