Antiretrovirals

Research from B.H. Chi and co-researchers yields new findings on antiretrovirals

Published in AIDS Weekly, October 12th, 2009

"Where virologic monitoring is not routinely available, immunologic criteria are commonly used to determine treatment failure while on antiretroviral therapy (ART). However, few have studied CD4(+) response and its relationship to subsequent clinical outcomes in a programmatic setting," scientists writing in the Jaids - Journal of Acquired Immune Deficiency Syndromes report.

"We analyzed cohort data from Zambia to investigate whether 6- and 12-month CD4(+) response after ART initiation was associated with later mortality. We used Cox proportional hazards models that accounted for different strata of baseline CD4(+) counts and adjusted for age, sex, clinical...

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Source: AIDS Weekly (2009-10-12)

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