HIV/AIDS

New findings from E.S. Gray and co-authors describe advances in HIV/AIDS

Published in AIDS Weekly, October 19th, 2009

"Defining the specificities of the anti-human immunodeficiency virus type 1 (HIV-1) envelope antibodies able to mediate broad heterologous neutralization will assist in identifying targets for an HIV-1 vaccine. We screened 70 plasmas from chronically HIV-1-infected individuals for neutralization breadth," investigators in Johannesburg, South Africa report.

"Of these, 16 (23%) were found to neutralize 80% or more of the viruses tested. Anti-CD4 binding site (CD4bs) antibodies were found in almost all plasmas independent of their neutralization breadth, but they mainly mediated neutralization of the laboratory strain HxB2 with little effect on the primary virus, Du151....

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Source: AIDS Weekly (2009-10-19)

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