HIV/AIDS

Research reports from University College provide new insights into HIV/AIDS

Published in AIDS Weekly, October 19th, 2009

According to recent research from Dublin, Ireland, "Neurons are one of the few cell types in the human body that do not support HIV type-1 (HIV-1) replication. Although the lack of key receptors is a major obstacle to infection, studies suggest that additional functions inhibit virus replication to explain the exquisite resistance of neurons to HIV-1."

"However, specific neuronal factors that may explain this resistance remain to be discovered. In a screen for antiviral factors using a fibroblast line chemically mutagenized and selected for resistance to retroviral infection, we recently identified induction of rat FEZ1 (fasciculation and elongation protein zeta-1), a...

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Source: AIDS Weekly (2009-10-19)

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