HIV/AIDS

Data on HIV/AIDS discussed by S. Banke and colleagues

Published in AIDS Weekly, October 19th, 2009

According to recent research published in the Journal of Virology, "Human immunodeficiency virus type 1 (HIV-1) protease inhibitors (PIs) specifically target the HIV-1 protease enzyme. Mutations in the enzyme can result in PI resistance (termed PI mutations); however, mutations in the HIV-1 gag region, the substrate for the protease enzyme, might also lead to PI resistance."

"We analyzed gag and pol sequence data from the following 313 HIV-1-infected patients: 160 treatmentna-Ove patients, 93 patients failing antiretroviral treatment that included a PI (with no major PI mutations), and 60 patients failing antiretroviral treatment that included a PI (with major PI...

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Source: AIDS Weekly (2009-10-19)

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