HIV/AIDS
Study findings from University of Washington provide new insights into HIV/AIDS
Published in AIDS Weekly, October 19th, 2009
According to a study from the United States, "We report on a proteomic analysis of ex vivo human immunodeficiency virus (HIV) type 1 infection in human primary CD4 cells by shotgun liquid chromatography-tandem mass spectrometry analysis, revealing two distinct proteomic profiles at two phases of virus replication. Relative to mock-infected cells, 168 signature proteins exhibited abundance changes at the first sign of Gag p24 production (8 h postinfection [p.i.]) or the peak of virus replication (24 h p.i.); interestingly, most of the changes were exclusive to only one phase of virus replication."
"Based on characterization by functional ontology and known human-HIV...
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Source: AIDS Weekly (2009-10-19)
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