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HIV/AIDS
Researchers from Harvard University, Medical Department detail new studies and findings in the area of HIV/AIDS
November 2nd, 2009
According to recent research from the United States, "Human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein modifications over the course of infection have been associated with coreceptor switching and antibody neutralization resistance, but the effect of the changes on replication and host cell receptor usage remains unclear. To examine this question, unique early-and chronic-stage infection envelope V1-toV5 (V1-V5) segments from eight HIV-1 subtype A-infected subjects were incorporated into an isogenic background to construct replication-competent recombinant viruses." "In all subjects, viruses with chronic-infection V1-V5 segments showed greater...
Source: AIDS Weekly (2009-11-02)
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