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AIDS Weekly

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HIV/AIDS



Studies from Royal Perth Hospital have provided new data on HIV/AIDS



November 2nd, 2009

"The effect of long-term antiretroviral therapy on serum immune activation markers was assessed in a cohort of 63 patients before and after 6 years of boosted lopinavir-based antiretroviral therapy," scientists writing in the Journal of Infectious Diseases report.

"High levels of most markers were associated with lower CD4(+) T cell counts at baseline and at year 6, with the exception of soluble cytotoxic T lymphocyte antigen-4 (sCTLA-4); high levels of sCTLA-4 were associated with higher CD4(+) T cell counts at year 6. Abnormalities of serum immune activation markers persisted after 6 years of ART but probably had different causes," wrote M.A. French and...


Source: AIDS Weekly (2009-11-02)

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