Hepatitis B Virus

Researchers from Nanjing Medical University provide details of new studies and findings in the area of hepatitis B virus

Published in AIDS Weekly, December 7th, 2009

"Chronic hepatitis B virus (HBV) infection is an important cause of cirrhosis and hepatocellular carcinoma. The major challenges for current therapies are the low efficacy of current drugs and the occurrence of drug resistant HBV mutations," researchers in Nanjing, People's Republic of China report.

"RNA interference (RNAi) of virus-specific genes offers the possibility of developing a new anti-HBV therapy. Recent reports have shown that lentiviral vectors based on HIV-1 are promising gene delivery vehicles due to their ability to integrate transgenes into non-dividing cells. Herein, a lentivirus-based RNAi system was developed to drive expression and delivery of...

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Source: AIDS Weekly (2009-12-07)

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