End Stage Renal Disease
Research on end stage renal disease described by scientists at Wake Forest University
Published in AIDS Weekly, January 4th, 2010
"Although MYH9 is strongly associated with biopsy-proven idiopathic and HIV-associated focal segmental glomerulosclerosis (FSGS) and clinically diagnosed 'hypertension-associated' end-stage renal disease (ESRD) in African Americans, its role in type 2 diabetes mellitus (T2DM)-associated ESRD is unclear. To assess whether MYH9 was associated with T2DM-ESRD, 751 African Americans with T2DM-ESRD, 227 with T2DM lacking nephropathy and 925 nondiabetic non-nephropathy controls were genotyped for 14 MYH9 SNPs," researchers in the United States report.
"Association analyses used SNPGWA and Dandelion. Comparing T2DM-ESRD cases with non-diabetic controls, single SNP associations...
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Source: AIDS Weekly (2010-01-04)
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