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Immunization

Findings in immunization reported from Erasmus University

Published in AIDS Weekly, January 11th, 2010

"Rabies vaccine was used as a T-cell-dependent neoantigen to investigate several aspects of the primary and booster immune response in vivo in HIV-infected individuals receiving antiretroviral treatment. Study participants received rabies vaccination twice, within a 3-month interval," investigators in Netherlands report.

"Serum samples were taken before and 1,2 and 4 weeks after both vaccinations and I and 5 years after the primary vaccination. Antirabies antibodies [immunoglobulin G (IgG), IgG subclasses, immunoglobulin A (IgA) and immunoglobulin M (IgM)] were determined; antibody avidity was measured after both vaccinations. T-cell subsets were characterized by flow...

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