Anti-Infectives

Studies from University of Wurzburg provide new data on anti-infectives

Published in AIDS Weekly, January 18th, 2010

According to recent research from Wurzburg, Germany, "In May 2007, the F. Hoffmann-La Roche Company became aware of a contamination of Viracept (nelfinavir) tablets by the mutagenic DNA-ethylating agent ethyl methanesulfonate (EMS) as a result of a production incident. HIV-patients could have been exposed for 3 months to daily doses of up to 2.75 mg EMS, i.e., about 50 mu g/kg per day."

"In this special issue, 12 manuscripts have been assembled to provide comprehensive insight in what happened and how the incident was managed by Roche and handled by the regulatory agencies. In the first four papers, the course of events and the toxicological information available at the...

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Source: AIDS Weekly (2010-01-18)

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