Monoclonal Antibodies

New monoclonal antibodies study findings have been reported from Y.S. Kap et al

Published in AIDS Weekly, January 18th, 2010

"Non-human primates (NHPs) offer valuable animal models for basic research into human diseases and for the preclinical validation of new therapeutics. Detailed in situ examination of the involved cell types using immunohistochemistry is often hampered by the lack of cross-reactive antibodies (Abs)," investigators in Netherlands report.

"In the current study, we have tested a large panel of monoclonal antibodies raised against human leukocyte differentiation and activation markers for cross-reactivity on cryosections of lymphoid tissue from six NHP species. In total, we have tested 130 Abs against 69 antigens expressed in tissues from one great ape species...

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Source: AIDS Weekly (2010-01-18)

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