Hepatitis B Virus

New hepatitis B virus data have been reported by scientists at University of Buenos Aires

Published in AIDS Weekly, January 25th, 2010

According to a study from Buenos Aires, Argentina, "The course of chronic HBV infection is modified by HIV-coexistence. To analyze the role of HBV genomic heterogeneity in basal core promoter (BCP) and precore (Pc) genomic regions."

"In a 3-yr prospective study, 39 HBV infected patients (20 monoinfected and 19 HIV-coinfected) were included. Eighty-two HBV isolates were studied at quasispecies level in the BCP/Pc genomic region. Clinical records obtained include data on lamivudine therapy and resistance mutations, HBV and HIV-viral load. HBV isolates were predominantly ascribed to genotype (Gt) A2 among HBV-monoinfected and HIV-coinfected patients. BCP mutations in...

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Source: AIDS Weekly (2010-01-25)

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