HIV/AIDS

Research in the area of HIV/AIDS reported from Fourth Military Medical University

Published in AIDS Weekly, February 8th, 2010

According to recent research from Xian, People's Republic of China, "It has recently been demonstrated that toll-like receptors (TLRs) can recognize structural conserved motifs carried by circulating microbial products and lead to systemic immune responses in individuals infected with HIV-1. TLRs have been detected in CD8(+)T cells at either a protein or RNA level."

"The role of TLRs on CD8(+)T cells involved in the host's immune responses during HIV-1 infection has not been well characterized. In this study, we analyzed expression of TLR4, TLR5, TLR7, and TLR8 in CD8(+)T cells in HIV-1 infection. All these four TLRs could be detected in CD8(+)T cells, but only TLR7 in...

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Source: AIDS Weekly (2010-02-08)

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