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Kidneys

Research from Kaiser Permanente reveals new findings on kidneys

Published in AIDS Weekly, February 15th, 2010

In this recent study, researchers in the United States conducted a study "To better characterize the long-term effects of tenofovir on renal function in a large managed care organization. We performed a retrospective cohort analysis in Kaiser Permanente for years 2002 to 2005 comparing renal function among antiretroviral naive patients initiating a tenofovir-containing regimen (964 patients) or tenofovir-sparing regimens (683 patients)."

"We evaluated glomerular filtration rate (GFR, (Modification of Diet in Renal Disease equation]), serum creatinine, and the development of renal proximal tubular dysfunction. We report multivariable hazard ratios (HR, Cox modeling) and...

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