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Investigators at University of Wisconsin, Wisconsin National Primate Research Center release new data on life sciences

Published in AIDS Weekly, March 1st, 2010

Researchers detail in 'Identification of novel MHC class I sequences in pig-tailed macaques by amplicon pyrosequencing and full-length cDNA cloning and sequencing,' new data in life sciences. According to a study from the United States, "Pig-tailed macaques (Macaca nemestrina) provide important animal models in biomedical research, but utility of this species for HIV and other disease pathogenesis research is limited by incomplete knowledge of major histocompatibility complex (MHC) class I genetics. Here, we describe comprehensive MHC class I genotyping of 24 pig-tailed macaques, using pyrosequencing to evaluate a 367-bp complementary DNA (cDNA)-PCR amplicon spanning the highly...

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