HIV/AIDS
University of Bordeaux details research in HIV/AIDS
Published in AIDS Weekly, March 8th, 2010
Data detailed in 'Evolution of 2-long terminal repeat (2-LTR) episomal HIV-1 DNA in raltegravir-treated patients and in in vitro infected cells' have been presented. "Our aim was to analyse the evolution of HIV-1 2-long terminal repeat (2-LTR) circular DNA in vitro and ex vivo in the presence of raltegravir. Twenty-five patients starting a raltegravir-based regimen were included," scientists writing in the Journal of Antimicrobial Chemotherapy report.
"Total HIV-1 DNA and 2-LTR DNA were quantified at baseline and in follow-up samples up to month 12. The effect of raltegravir on the formation of 2-LTR circles was evaluated in HeLa P4 cells. The effect of...
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Source: AIDS Weekly (2010-03-08)
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