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HIV/AIDS Vaccine

Data on HIV/AIDS vaccine published by researchers at University of New Mexico

Published in AIDS Weekly, March 22nd, 2010

New research, 'Induction of mucosal and systemic antibody responses against the HIV coreceptor CCR5 upon intramuscular immunization and aerosol delivery of a virus-like particle based vaccine,' is the subject of a report. According to recent research from the United States, "Virus-like particles (VLPs) can be exploited as platforms to increase the immunogenicity of poorly immunogenic antigens, including self-proteins. We have developed VLP-based vaccines that target two domains of the HIV coreceptor CCR5 that are involved in HIV binding."

"These vaccines induce anti-CCR5 antibodies that bind to native CCR5 and inhibit SIV infection in vitro. Given the role of mucosal...

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