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HIV/AIDS Vaccine

Scientists at AIDS Center report research in HIV/AIDS vaccine

Published in AIDS Weekly, March 22nd, 2010

Scientists discuss in 'The preventive phase I trial with the HIV-1 Tat-based vaccine' new findings in HIV/AIDS vaccine. "The native HIV-1 Tat protein was chosen as vaccine candidate for phase I clinical trials based on its role in the natural infection and AIDS pathogenesis, on the association of Tat-specific immune response with the asymptomatic stage as well as on its sequence conservation among HIV clades. A randomized, double blind, placebo-controlled phase I study (ISS P-001) was conducted in healthy adult volunteers without identifiable risk of HIV infection," scientists writing in the journal Vaccine report.

"Tat was administered 5 times monthly, subcute...

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