Ritonavir Therapy

New ritonavir therapy study findings reported from K.W. Garren and co-authors

Published in AIDS Weekly, March 22nd, 2010

According to recent research published in the Journal of Pharmaceutical Sciences, "In this study, we explored the bioavailability in dogs and chemical potency of generic ritonavir and lopinavir/ritonavir tablet products manufactured by various pharmaceutical companies. Chemical potency of the products was examined by HPLC quantitation of ritonavir and lopinavir."

"Using a dog model, we determined point estimates for C-max and AUC of ritonavir and lopinavir/ritonavir for eight generic products compared to Abbott's Norvir ® capsule and Kaletra ® tablet. Chemical potencies ranged from 79.0% to 104.6%. Point estimates for AUC in the generic tablet products...

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Source: AIDS Weekly (2010-03-22)

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