Tuberculosis Vaccines
New tuberculosis vaccines study results from University Medical Center, Department of Infectious Diseases described
Published in AIDS Weekly, April 5th, 2010
A new study, 'Mycobacterium tuberculosis peptides presented by HLA-E molecules are targets for human CD8 T-cells with cytotoxic as well as regulatory activity,' is now available. "Tuberculosis (TB) is an escalating global health problem and improved vaccines against TB are urgently needed. HLA-E restricted responses may be of interest for vaccine development since HLA-E displays very limited polymorphism (only 2 coding variants exist), and is not down-regulated by HIV-infection," scientists writing in the journal PLoS Pathogens report.
"The peptides from Mycobacterium tuberculosis (Mtb) potentially presented by HLA-E molecules, however, are unknown. Here...
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Source: AIDS Weekly (2010-04-05)
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