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Duke University Medical Center

Scientists identify how a novel class of antibodies inhibits HIV infection

Published in AIDS Weekly, April 19th, 2010

Scientists at Duke University Medical Center have identified a set of naturally occurring antibodies that can block one of the key ways the AIDS virus gains entry into certain blood cells. They say the discovery, published online in the Journal of Experimental Medicine, expands traditional notions about how the immune system fights HIV and offers a potential new strategy for HIV vaccine design.

Researchers have been puzzled and frustrated for years by antibody responses to HIV. In most infections, antibodies that fight off invading pathogens show up quickly and get right to work. But with HIV, the most powerful antibodies typically don't materialize until weeks or even...

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