Published in AIDS Weekly, April 19th, 2010
"AID-mediated SHM in B cell lines can be used to generate patient's HIV-1 envelope protein diversity in vitro for subsequent vaccination of HIV-1-infected patient at the beginning of asymptomatic period with a resulting mixture of mutant envelope proteins," wrote K.V. Suslov and colleagues.
The researchers concluded: "Suggested approach, which represents a vaccination against R5-X4 HIV-1 switching, might open possibilities for creation of patient-specific therapeutic HIV vaccines based on induction of...
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Source: AIDS Weekly (2010-04-19)
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