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HIV/AIDS Vaccine

New HIV/AIDS vaccine study findings recently were published by K.V. Suslov and co-researchers

Published in AIDS Weekly, April 19th, 2010

According to a study from Russia, "The somatic hypermutation (SHM) hypothesis for R5-X4 HIV-1 switching has recently received experimental support."

"AID-mediated SHM in B cell lines can be used to generate patient's HIV-1 envelope protein diversity in vitro for subsequent vaccination of HIV-1-infected patient at the beginning of asymptomatic period with a resulting mixture of mutant envelope proteins," wrote K.V. Suslov and colleagues.

The researchers concluded: "Suggested approach, which represents a vaccination against R5-X4 HIV-1 switching, might open possibilities for creation of patient-specific therapeutic HIV vaccines based on induction of...

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