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Highly Active Antiretroviral Therapy

Study data from Johns Hopkins University update understanding of highly active antiretroviral therapy

Published in AIDS Weekly, April 19th, 2010

A new study, 'Minocycline attenuates HIV infection and reactivation by suppressing cellular activation in human CD4+ T cells,' is now available. According to recent research published in the Journal of Infectious Diseases, "Treatment of human immunodeficiency virus (HIV) infection with highly active antiretroviral therapy (HAART) is effective but can be associated with toxic effects and is expensive. Other options may be useful for long-term therapy."

"The immunomodulatory antibiotic minocycline could be an effective, low-cost adjunctive treatment to HAART. Minocycline mediated a dose-dependent decrease in single-cycle CXCR4-tropic HIV infection and decreased...

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